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University of Lille

The University of Lille is a multi-disciplinary university of Excellency based in the north of Europe.  The University can count on an exceptional cultural and scientific patrimony inscribed in the Hauts de France region.

The University of Lille is one of the main actor in the region in terms of formation, research and innovation.

Over the past years, the University of Lille has increasingly placed its international outlook at the heart of its administration, academic programmes and research. As the laureate in 2017 of a vast national program to fund academic excellence (I-SITE), the University of Lille is committed to organizing its international programmes around selected research strands, international student recruitment methods and high-quality international partnerships.

STRUCTURED, HIGH LEVEL RESEARCH

The University of Lille houses 66 laboratories and research units covering all fields of study. The quality of its research has been widely recognized on the national level through the awarding of prestigious labels and funding: an I-SITE project, seven research facilities of excellence (EQUIPEX) and five laboratories of excellence (LABEX).

The university’s many research groups, networks and facilities contribute to effective multidisciplinary research, as well as to its valorisation via socio economic partnerships. These projects include an integrated cancer research site (SiricOncolille), an institute for energy transition (ITE) and a technology transfer group (SATT). The university belongs to a network including five technology parks and seven competitiveness clusters, which allows businesses and laboratories to collaborate on innovation in cutting-edge sectors.

The University of Lille has high-level research facilities covering a wide range of fields such as physics, chemistry, information and technology sciences and health sciences.

Research is supported by joint research institute as the Michel-Eugène Chevreul Institute. It is a Research Federation which brings together four Research Units from the Hauts-de-France region working in the field of Chemistry and Materials.  The Chevreul Institute has several advanced characterization platforms at the cutting edge of technology open to academic and partnership research or to services for actors in the socio-economic world including: NMR, electronic microscopy, X-Ray diffraction, surface analysis, vibrational spectroscopy, mass spectroscopy, electronic paramagnetic resonance.

PARTNERS AND NETWORKS

The university international ambition is put into practice through institutional networks and agreements, particularly within the European Universities Association (EUA), Agenceuniversitaire de la Francophonie (AUF), Institut des Amériques, the French-Dutch Network and Campus France, an organisation established by the French government to promote French higher education abroad. It is also a member of several international student exchange programmes: the International Student Exchange Programs (around 60 different countries), the France-Quebec Interuniversity Cooperation Office, the Erasmus + programme. It also collaborates with institutions in other countries through numerous bilateral agreements. It has also established structured partnerships with several consortia of universities.

BIOPHAM KEY STAFF

At the University of Lille, the key staffs involved in the BIOPHAM programme are Professors and Researchers from the Faculty of Sciences and Technology (Physics Department) and from the Faculty of Pharmacy.  The courses dedicated to track 2 “condensed-matter and pharmaceuticals” that will be offered in the 3rd semester of the BIOPHAM Master will be thus jointly delivered by physicists and pharmacists. The multidisciplinary aspect of the Master requires teachers from different fields in order to propose expert courses for the students. Specialized courses will focus on the different materials (active pharmaceutical ingredients and excipients) used in pharmacy, their physical states, their specific modes of preparation and transformation induced by the typical constraints imposed by industrial processes. The students will also gain a thorough understanding of specific numerical atomistic methods and mathematical modelling approaches suitable for the study of these materials. The teaching will be illustrated by examples encountered in the pharmaceutical industries (and also food and cosmetics industries). It will be a multidisciplinary education at the interface between materials science and pharmacy underlying research and development of pharmaceutical formulations.  All professors are also researchers and work closely with industrials partners i.e. they are all highly recognized in their own field and they are up to date in current scientific knowledge. This will allow continuous adjustment of the courses content in relation to day-to-day discoveries. All professors and researchers belong to two research teams: the “Therapeutically Molecular Materials” team which is part of the Materials and Transformations Unit (UMET) UMR 8207 laboratory. Research unit jointly administered by the University of Lille and the French National Council of Scientific Research, CNRS and the “Advanced Drug Delivery Systems” group INSERM U1008 and a team jointly administered by the University of Lille and the French National Institute of Health and Medical Research).

Prof. Siepmann studied Pharmacy at the University of Angers, France, and did her Ph.D. at the Freie Universitaet Berlin, Germany, on polymeric controlled drug delivery systems. Since 2016 she is Professor of Pharmaceutical Technology at the University of Lille, France. Her research focuses on Controlled Drug Delivery Systems, in particular on the elucidation of the underlying mass transport phenomena and the optimization of the devices. A special focus is placed on biodegradable microparticles and in-situ forming implants. So far, she published her work in more than 130 articles in international scientific journals and more than 240 poster and 50 oral presentations at scientific meetings.

Since 2011, she is member of the council of the “International Society of Drug Delivery Sciences and Technology” (APGI) (https://www.apgi.org). Since 2016 Prof. Siepmann serves as Editor-in-Chief of the "Journal of Drug Delivery Science and Technology" (https://www.journals.elsevier.com/journal-of-drug-delivery-science-and-technology). She is also co-director of the INSERM U1008 research group "Advanced Drug Delivery Systems" (http://u1008.univ-lille2.fr). Currently, the research group counts about 50 members (15 professors/senior lecturers, 5 technical staff, 20 post-docs/PhD students and 10 master students.

ORCID : 0000-0001-6337-0234

Professor Frédéric Affouard, main coordinator of the BIOPHAM programme, is a physicist member of the “Therapeutical Molecular Materials group since 2010 and presently Deputy-director of the UMET laboratory. He obtained his Ph.D. at the University Paris-Diderot in 1994 and then performed a post-doctoral position at the Technical University of Berlin. His research activities are dedicated to the physical states of pharmaceutical molecular materials (small organic molecules, polymers and biomolecules) and their transformations including molecular modelling approaches. He is presently the Principal Investigator (PI) of the large European 2 Seas INTERREG IMODE research project gathering 10 partners from academia and industry (France, UK and Belgium) which have joined their skills to develop innovative multi-component drugs and medical devices (6M€). The research “Therapeutical Molecular Materials” group has been financially supported by industrial partners (e.g. Sanofi, Astrazeneca, Servier, Roquette) and institutional partners (e.g. French research ministry, University of Lille, North of France Region).

ORCID: 0000-0001-8429-6416  

Emeline Dudognon is assistant Professor of Physics at the University of Lille and is part of the "Unité Matériaux Et Transformations" (UMET) laboratory. Her research activities focus on the physical states and the phase transformations of organic compounds (small molecules and polymers) of pharmaceutical interest, as well as the dynamics of glass-forming liquids. She is a specialist of dielectric relaxation spectroscopy.

ORCID: 0000-0003-4176-1925

Natalia Correia  is assistant Professor of Physics at the University of Lille and belongs to the "Unité Matériaux Et Transformations" (UMET) laboratory. Her research activities focus on the investigations of phase transformations and slow relaxation processes in pharmaceutical and agro-chemical materials using various complementary techniques. She particularly investigates relations between these relaxations and the nucleation and crystallization process. N. Correia is also specialist of amorphization processes of therapeutic materials and the influence of confinement on state diagrams and dynamics.

Techniques: Dielectric Relaxation Spectroscopy (DRS), Thermally Stimulated Depolarisation Currents (TSDC), Infra-red spectroscopy (FTIR), Differential Scanning Calorimetry (DSC), Dynamical Mechanical Spectroscopy (DMA), X-ray diffraction.

Emilie Toulet is Head of Office for the International relations at the Faculty of Sciences and Technologies. She has a long experience in managing international programmes and has been involved in many Erasmus+ and Erasmus Mundus projects (ASC, Bioref and Pangea) in a wide range of fields.

Juergen Siepmann studied Pharmacy and did his Ph.D. at the Freie Universitaet Berlin, Germany. Since 2004 he is Professor of Pharmaceutical Technology at the University of Lille, France.
In 2006 Prof. Siepmann created the “Young research group: Controlled Drug Delivery Systems”, which became the “INSERM research group: Advanced Drug Delivery Systems” in 2010 (INSERM = French National Institute of Health and Medical Research). The team currently counts about 50 scientists: 9 professors, 6 senior lecturers, 7 technical/administrative staff, and about 20 post-docs/PhD students & 10 master students. Prof. Siepmann’s research focuses on controlled drug delivery systems, in particular on the elucidation of the underlying mass transport phenomena, mathematical modeling and the optimization of the devices. So far, he published his work in more than 180 articles in international scientific journals, 325 poster and 140 oral presentations at national and international scientific meetings. He is editor of 3 books, theme editor of 9 special issues, inventor of 9 patents and author of 17 book chapters. His awards include the “APV-Prize for the outstanding doctoral thesis in Pharmaceutical Sciences from the years 1998/99”, a Marie Curie Individual Post-Doctoral Fellowship and the “2012 APV Research Award for Outstanding Achievements in the Pharmaceutical Sciences”. Prof. Siepmann was visiting scientist/postdoctoral fellow at Purdue University, the University of Paris-Sud, the University of Iowa and the University of Angers.

Since 2010 he serves as president of the “International Society of Drug Delivery Sciences and Technology” (APGI) (https://www.apgi.org). The APGI was created in 1964 in Paris, and is an association for scientists in academia and industry, who are concerned with pharmaceutical technology and the design, formulation as well as biopharmaceutical and pharmacokinetic assessment of dosage forms and drug delivery systems.

 Currently, Prof. Siepmann is also the coordinator of the Interreg project “Site Drug: Site-Specific Drug Delivery” (https://site-drug.org). The consortium counts 10 European Universities and companies. The aim is to develop innovative drug delivery systems for improved local drug treatments.

Since 2016, Prof. Siepmannalso serves as Editor-in-Chief of the International Journal of Pharmaceutics(http://ees.elsevier.com/ijp), according to the Web of Science a “top 1% journal” in terms of citation share in the field of “Pharmacology and Pharmacy” (ranked #3 out of 270 journals).