Examples of research projects carried out by former students during their Master’s thesis, illustrating the broad diversity of topics addressed within the programme.

Efficacy and safety testing of empty and drug-loaded solid lipid nanoparticles for glioblastoma treatment

Molecular relaxation dynamics of amorphous Terfenadine and its kinetic of crystallization from the supercooled liquid state.

Numerical prediction of the glass transition of pharmaceuticals:insight from MD simulations

Physico-chemical state and solubility of antidiabetic drug within the polymer matrix

3D bioprinting of a vascularized myogenic tissue using spheroids: towards an enhanced complexity of in vitro-engineered muscles

3D printed oral solid dosage forms with dose combinations

3D printing of bioresorbable drug eluting stents

Advanced Biomimetic Materials: Mechanical Evaluation of Supramolecular Peptide Amphiphile Hydrogels

Advanced Characterization of Protein Misfolding and Pathological Assembly in Neurodegenerative Diseases

An epidemiological model for malaria that accounts for gene deletions

Analysis of biological effects of heme or heme precursor delivery to developing mouse embryos

Analysis of drug-loaded materials for FDM 3D printing of personalized solid oral dosage forms

Antibacterial coatings using green materials  and technologies

Atomistic modeling of the interactions betweenthe PNIPAAm thermosensitive hydrogel and the PEDOT conducting polymer

Atomistic modelling of thermosensitive hydrogels

Binary mixtures for improving solubility of naproxen

Carbon nitride-based nanomaterials:  Investigation of the antibiotics photodegradation in environment

Carbon Quantum Dots doped  PEDOT for Sensing Applications

Collecting secretome of Mesenchymal stem cells

Cytotoxicity and Cell Death Evaluation of Quninazoline  Derivative Against Breast Carcinoma Cell line

Design and characterization of cocrystals of pharmaceutical interest by green synthesis methods

Designing nanoparticles to intranasally deliver nanobodies targeting Aβ peptides to the brain

Development and characterization of luminescent nanosensors for imaging in microalgae cells

Development of 3D in vitro cancer models  for precision medicine approaches

Development of a microgel as a 3D environment for tumour cell culture

Development of aptamer-modified biomedical sensors

Development of cell-permeable ligands to the intracellular cancer target β-catenin by high-throughput synthesis and screening of large combinatorial cyclic peptide libraries

Development of complex in vitro model to study anti-diabetic drugs

Development of computational models of the dynamics of transmembrane ion channels.

Development of functionalized  antimicrobial surfaces

Development of Oral Controlled drug delivery systems in the distal part of GIT

Dielectric relaxations of amorphousimidazole-based antifungal/antibiotics and their binary mixtures

Dielectric relaxaton in amorphous imidazole-based antifungal and antibiotic drugs

Drug release in different types of hydrogels embedded in nanotubes for nerve regeneration

Effect of alkyl chain length on phase transitions and ion dynamics of phosphonium ionic liquids at ambient and elevated pressure

Effect of perfume on the stability of liquid fabric enhancer

Effects of the fraction of ischemia leading to re-entry in cardiac tissue

Efficacy and safety testing of empty and drug loaded polymeric nanoparticles for glioblastoma treatment

Elaboration of biocompatible conductive hydrogels by 3D printer for the development of (bio)sensors

Elucidating the variability of neuronal recruitment during spontaneous activity in a conserved neural circuit

Engineering a novel hypoxic biologically complex 3D in vitro model of the pancreatic cancer stroma.

Enzymatic polymerization of dopamine to produce poly(dopamine)-based coatings for potential biomedical applications

Exploration of amorphous quantification of an active pharmaceutical ingredient (API) by Dynamic Vapour Sorption (DVS)

Exploration of non-conventional amorphous formulations (co-amorphous, confinement in porous materials) to improve physical stability of a bad glass-former

Extensional Rheology and Stability of Electrospinning Operations for Biopolymer Solutions

Fabrication of oligomer-crosslinked chitosan microparticles

Fitting of complex models of infectious disease with a simple SIRS model

Formulation and characterization of biodegradable implant using 3D printing technique

Formulation and physicochemical characterization of biodegradable microparticles with controlled release

Formulation in the amorphous state

From vapor to crystal nucleation: a study of the dynamics of single-step and multi-step nucleation mechanisms

Glass transition in highly stable organic glasses

Glass transition. relaxation dynamics. and H2O-induced effects in an amorphous lyophilizcd protein

glass-transition dynamics and crystallization behavior of non-opioid analgesic and antipyretic agent paracetamol in the bulk and nanopore-confinement

Green solvents and processes to improve cellulose based biomedical packaging

How nutrient concentration and wettability of the agar substrate influence the mature curli fiber conformation produced by E. coli W3110

Identification and genomic characterization of bacteriocins

In silico chemistry and physics of reconstruction of oxide surfaces in contact with liquid water by ab initio molecular dynamics simulations (DFT-MD)

Investigating Hydrophobic Hydration using Molecular Dynamics

Investigation of Stable and Metastable States of 4-Methylbenzophenone Using DSC and XRD

Investigations of amorphous compounds obtained by different amorphization processes

Iron complexes. Synthesis, analysis and their properties in the cell biology context.

Kinetics of the polymorphic transformation of sulfamerazine upon milling

Mechanical properties of Pharmaceuticals from simulations

Microfluidics for Engineering of Lipid-Based Nanoparticles

Miniaturised implants for inner ear delivery

Modeling Biochemical polarization and locomotion of living cells

Modeling of the dynamics of fibroblast during capsulation of tuberculosis infections

Modeling polymer-based materials for sustainable processes

Modelling of the competition between season respiratory infectious disease

Molecular Dynamics of Adamantanone

Multi-material volumetric 3D printing of cell-interactive implants for hard tissue engineering

Non-Rigid Point Cloud Registration using Texture Information

Nucleation of drug polymorphs in solution: Investigation from atomistic simulations

Optimisation of alginate capsules to generate bone marrow hematopoietic stem cell niche

Optimization of the Novel Production Protocols for the Drug Delivery Systems

Optimization of the physical stability of pharmaceutical amorphous molecular dispersions

Oral controlled drug delivery systems for oral administration

Personalisation of solid dosage forms using 3D printing of solid dispersions

Personalized cancer therapy assessment in 3D advanced in vitro models of sinonasal tumors

Physical aging of complex amorphous systems in-situ through solid-state method development enabling sample environmental history evaluation and prediction of stability.

Polymorphic forms of Fluconazole: Thermal and Crystallographic Characterization

Polymorphism of Drugs

Preparation and evaluation of SEDDS (Self Emulsifying Drug Delivery Systems) for two selected active ingredients (Itraconazol and Naproxen): optimization of the formulation development method

Preparation of co-amorphous formulations of bad glass-formers and physical stability evaluation

Probiotic encapsulation in biomaterials for bacteriotherapy

Probiotic encapsulation in biomaterials for bacteriotherapy

Reflection of single water molecules from liquid and solid water interfaces

Role of adhesive matrix in architecture bacterial biofilms

Squalene-based nanoparticles for the treatment of cancer-induced bone pain

Stability and Modification of the crystallography of active pharmaceutics ingredients (API) by cocrystallization and milling

Stability of biopharmaceuticals during freezing/thawing and freeze-drying: small-angle neutron scattering (SANS) investigation of structure of lipid nanoparticles for drug delivery systems

Stability of proteins in extreme conditions

Structural Features of Hydrogels based on Hyaluronic Acid

Study of the physical state of pharmaceutical materials under high energy milling and high pressures

Synthesis and characterization of Nickel-Copper alloy nanoparticles

Synthesis and Characterization of Particles Coupling Fe MOFs and Gold Clusters for Drug Delivery

Temperature-dependent conductivity and water-induced effects in amorphous and crystalline orcinol

Therapeutic nanocrystal formulations and characterization for better stability and efficacy

Thermal and dynamic properties and a release study of the curcumin in DL-PADAS

Transmission electron microscopy and electron diffraction  for pharmacological products characterization

Understanding nanoscale dynamics in multicomponent pharmaceutical systems

Use of PLA nanofiber incorporated Hydrogels as scaffolds for the regeneration of Cardiac tissue

Use of synchrotron radiation for the  study of biocompatible metallic glasses